The Sleep and Circadian Research Group is focused on understanding the impact of sleep disorders on health and well-being, and developing new diagnostic and therapeutic pathways to improve sleep health. The Group’s work spans several key research areas including: Neurobiology, Neurodegeneration and Sleep; Insomnia and Behavioural Sleep Medicine; Chronic Respiratory Disease and Sleep; Cardiometabolic Diseases and Sleep; and Epidemiology and Clinical Trials. The Woolcock has a suite of state-of-the-art research facilities including high-density electroencephalography and the ‘Australian Centre for Chronobiology, Endocrinology and Sleep Sciences Laboratory’ – a sleep lab which can be operated in time isolation mode, with varying light intensity and light spectra and controlled noise exposure.
Current examples of some of the research studies include: An app-delivered sleep therapy for older individuals with insomnia; severe obstructive sleep apnea and changes in certain markers of dementia; effects of an orexin agonist in people with narcolepsy (with and without cataplexy) and idiopathic hypersomnia; a weight loss drug trial for excess weight in people with Diabetes Type 2 with or without obstructive sleep apnea; and investigating the brain’s waste management system in patients with severe OSA.
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CIRUS, the Centre for Sleep and Chronobiology conducts patient-centred translational research across a broad spectrum of sleep disorders at the Woolcock Institute of Medical Research, University of Sydney and at partner sites within Sydney, across Australia and internationally.
CIRUS is a sophisticated network of organisations, clinical services, research leaders and facilities which conducts research in a range of areas through a multi-site collaborative approach, utilising the strengths of each partner. Its collective capacity and interdisciplinary methodology fosters new discoveries in science and medicine which are then translated to improved sleep healthcare.